Can you re-enable areas once used?

[Nevicar]

Example:
There is a room where the player walks into, the door behind them closes as they enter via a script, but then don't collect the item from the room and has to come back to it. Is it possible to have the area reset and have it activate again when the player passes through it in an event that happens later in the level on the way to the end of the level?

I... think that's clear.