Can HPL2 do this? (Texture swapping based on camera)

[Arkham]

Peripheral vision, therefore, would have to be achieved using script areas that are larger than the object it is associated with or placed somewhere on the sides of the object. This means taking into consideration the user's window resolution.

Do you mean there would have to be differently-sized script areas for every possible monitor resolution (daunting, and maybe impossible if Amnesia supports custom resolutions)?
Or do you mean there would have to be different ones based on possible monitor ratios, i.e. 5:4, 16:9, 16:10 (which seems a lot more doable)?