Famale Charchters in Videogames: The Opposite of "attractive" would it work?

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how can it be a stereotype though when its based 100% on real people? you would be surprised how many aspergirls meet that description, just take 5 minuites on wrong planet. im confused how reality can be seen as a
sterotype?

Stereotypes often have a grounding in reality - that's how they come into existence. By taking the character traits of one "extreme" member of a group (women in this case) and assuming that all members of said group have them.

The main problem is, however, that it could be perceived the wrong way. If your character was a man who'd have the same character traits, it might be easier to get the actual point across - that is raising awareness for the dificulties people with aspergers have.
But unfortunately, many of those asperger and autism traits you mentioned are also associated with very negative and very old stereotypes about women (being insecure, easily frightened, dependend on other people, being very emotional and easily bursting into tears...). Therefore your original point could get lost, because people might misunderstand what you are trying to say by including that character.

Like I said, if you were to make it very clear that her characteristics do not stem from her being a woman but from something entirely different, it could work....but the risk of it being misunderstood is always there I guess.