New Game Design/Gameplay needed for dealing with Enemies in future games

[Radiance]

Yes, here I absolutely agree with you.

I think that is for the first time.
But, I also mean to built/create concoctions, mixtures and liquids for manipulating the creatures and environment.
I suppose you wouldn't like that.

Am I right that you mean using scraps in the environment to build your way out? This is something I like in the Penumbra games. Puzzles based on interactions and physics.

Yeah, but not overuse same mechanics. In SOMA this was used only once close to the end.