SPOILERS AHEAD!
Can anybody help me?
I am playing the Mac version.
I am just up to the part where I am chased by the monster in the sewer, I have to go through and slam shut two doors so I can get to the ladder leading upwards.  I get a loading screen when I get a certain way up the ladder, but then it unexpectedly quits to the desktop.  I've tried it about three times now with the same result.
The second time I made a save while I was on the ladder before I got too high.  I found the bit with the monster quite difficult and didn't want to have to do it again.  It quit to the desktop again as soon as it finished saving, but luckily, it loaded up again OK so I was on the ladder.
So I tried climbing the ladder again, and got the loading screen and then once again, it unexpectedly quit to the desktop.  I had error messages on all three occasions.
I have copied and pasted below the error message I got on my final attempt (after the mid-ladder loading screen).
Process:         Amnesia [362]
Path:            /Applications/AMNESIA - THE DARK DECENT/Amnesia.app/Contents/Resources/Amnesia.app/Contents/MacOS/Amnesia
Identifier:      com.frictionalgames.Amnesia
Version:         1.0 (1)
Code Type:       X86 (Native)
Parent Process:  launchd [79]
Date/Time:       2010-09-18 01:54:41.392 +0100
OS Version:      Mac OS X 10.6.4 (10F569)
Report Version:  6
Interval Since Last Report:          578714 sec
Crashes Since Last Report:           4
Per-App Interval Since Last Report:  71243 sec
Per-App Crashes Since Last Report:   4
Anonymous UUID:                      86D0B707-CF37-4326-9F07-C4DD62EAFDC9
Exception Type:  EXC_CRASH (SIGSEGV)
Exception Codes: 0x0000000000000000, 0x0000000000000000
Crashed Thread:  1  Dispatch queue: com.apple.libdispatch-manager
Thread 0:  Dispatch queue: com.apple.main-thread
0   com.frictionalgames.Amnesia   	0x003c2a8d std::_Rb_tree<std:

tring, std::pair<std:

tring const, int>, std::_Select1st<std::pair<std:

tring const, int> >, std::less<std:

tring>, std::allocator<std::pair<std:

tring const, int> > >::find(std:

tring const&) + 77
1   com.frictionalgames.Amnesia   	0x0030b74f hpl::cMeshEntity::GetAnimationStateIndex(std:

tring const&) + 31
2   com.frictionalgames.Amnesia   	0x0030bb98 hpl::cMeshEntity:

layFadeToName(std:

tring const&, bool, float) + 56
3   com.frictionalgames.Amnesia   	0x001ee951 cLuxPlayerHands:

layAnim(std:

tring const&, bool) + 49
4   com.frictionalgames.Amnesia   	0x001eea0b cLuxPlayerHands::SetCurrentHandObject(iLuxHandObject*) + 155
5   com.frictionalgames.Amnesia   	0x001559bc cLuxPlayerLantern::SetActive(bool, bool, bool, bool) + 172
6   com.frictionalgames.Amnesia   	0x001fb6da cLuxPlayerState_Ladder::OnLeaveState(eLuxPlayerState) + 154
7   com.frictionalgames.Amnesia   	0x001103c0 cLuxPlayer::ChangeState(eLuxPlayerState) + 48
8   com.frictionalgames.Amnesia   	0x0011201e cLuxPlayer::OnMapLeave(cLuxMap*) + 30
9   com.frictionalgames.Amnesia   	0x001b3ec0 cLuxBase::RunModuleMessage(eLuxUpdateableMessage, void*) + 176
10  com.frictionalgames.Amnesia   	0x0010c673 cLuxMapHandler::SetCurrentMap(cLuxMap*, bool, bool, std:

tring const&) + 115
11  com.frictionalgames.Amnesia   	0x0010cdb1 cLuxMapHandler::CheckMapChange(float) + 577
12  com.frictionalgames.Amnesia   	0x0010d2b0 cLuxMapHandler::Update(float) + 48
13  com.frictionalgames.Amnesia   	0x003e432d hpl::cUpdater::RunMessage(hpl::eUpdateableMessage, float) + 653
14  com.frictionalgames.Amnesia   	0x00291643 hpl::cEngine::Run() + 355
15  com.frictionalgames.Amnesia   	0x001418c4 hplMain(std:

tring const&) + 68
16  com.frictionalgames.Amnesia   	0x002f3f67 SDL_main + 327
17  com.frictionalgames.Amnesia   	0x002393f2 -[SDLMain applicationDidFinishLaunching:] + 66
18  com.apple.Foundation          	0x900191c3 _nsnote_callback + 176
19  com.apple.CoreFoundation      	0x91aec3c3 __CFXNotificationPost + 947
20  com.apple.CoreFoundation      	0x91aebdca _CFXNotificationPostNotification + 186
21  com.apple.Foundation          	0x9000e090 -[NSNotificationCenter postNotificationName:object:userInfo:] + 128
22  com.apple.Foundation          	0x9001b46d -[NSNotificationCenter postNotificationName:object:] + 56
23  com.apple.AppKit              	0x96c7770a -[NSApplication _postDidFinishNotification] + 125
24  com.apple.AppKit              	0x96c7761a -[NSApplication _sendFinishLaunchingNotification] + 74
25  com.apple.AppKit              	0x96dce6a9 -[NSApplication(NSAppleEventHandling) _handleAEOpen:] + 274
26  com.apple.AppKit              	0x96dce2c9 -[NSApplication(NSAppleEventHandling) _handleCoreEvent:withReplyEvent:] + 101
27  com.apple.Foundation          	0x9004e400 -[NSAppleEventManager dispatchRawAppleEvent:withRawReply:handlerRefCon:] + 511
28  com.apple.Foundation          	0x9004e1c4 _NSAppleEventManagerGenericHandler + 228
29  com.apple.AE                  	0x993f2f58 aeDispatchAppleEvent(AEDesc const*, AEDesc*, unsigned long, unsigned char*) + 166
30  com.apple.AE                  	0x993f2e57 dispatchEventAndSendReply(AEDesc const*, AEDesc*) + 43
31  com.apple.AE                  	0x993f2d61 aeProcessAppleEvent + 197
32  com.apple.HIToolbox           	0x9585b323 AEProcessAppleEvent + 50
33  com.apple.AppKit              	0x96c47cc6 _DPSNextEvent + 1420
34  com.apple.AppKit              	0x96c472ca -[NSApplication nextEventMatchingMask:untilDate:inMode:dequeue:] + 156
35  com.apple.AppKit              	0x96c0955b -[NSApplication run] + 821
36  com.frictionalgames.Amnesia   	0x00239b20 main + 1488
37  com.frictionalgames.Amnesia   	0x0006babe start + 54
Thread 1 Crashed:  Dispatch queue: com.apple.libdispatch-manager
0   libSystem.B.dylib             	0x91911942 kevent + 10
1   libSystem.B.dylib             	0x9191205c _dispatch_mgr_invoke + 215
2   libSystem.B.dylib             	0x91911519 _dispatch_queue_invoke + 163
3   libSystem.B.dylib             	0x919112be _dispatch_worker_thread2 + 240
4   libSystem.B.dylib             	0x91910d41 _pthread_wqthread + 390
5   libSystem.B.dylib             	0x91910b86 start_wqthread + 30
Thread 2:
0   libSystem.B.dylib             	0x918eb15a semaphore_timedwait_signal_trap + 10
1   libSystem.B.dylib             	0x91918ca5 _pthread_cond_wait + 1066
2   libSystem.B.dylib             	0x91947848 pthread_cond_timedwait_relative_np + 47
3   com.apple.audio.CoreAudio     	0x909e4805 CAGuard::WaitFor(unsigned long long) + 219
4   com.apple.audio.CoreAudio     	0x909e7837 CAGuard::WaitUntil(unsigned long long) + 289
5   com.apple.audio.CoreAudio     	0x909e5134 HP_IOThread::WorkLoop() + 1892
6   com.apple.audio.CoreAudio     	0x909e49cb HP_IOThread::ThreadEntry(HP_IOThread*) + 17
7   com.apple.audio.CoreAudio     	0x909e48e2 CAPThread::Entry(CAPThread*) + 140
8   libSystem.B.dylib             	0x9191881d _pthread_start + 345
9   libSystem.B.dylib             	0x919186a2 thread_start + 34
Thread 3:
0   libSystem.B.dylib             	0x918eb20e mach_wait_until + 10
1   libSystem.B.dylib             	0x919725a9 nanosleep + 345
2   SDL                           	0x00bc3453 SDL_Delay + 99
3   com.frictionalgames.Amnesia   	0x00269840 UpdaterThread(void*) + 64
4   SDL                           	0x00bb4ecd SDL_Linked_Version + 397
5   SDL                           	0x00bc31f1 SDL_SemWait + 49
6   libSystem.B.dylib             	0x9191881d _pthread_start + 345
7   libSystem.B.dylib             	0x919186a2 thread_start + 34
Thread 4:
0   libSystem.B.dylib             	0x919109d2 __workq_kernreturn + 10
1   libSystem.B.dylib             	0x91910f68 _pthread_wqthread + 941
2   libSystem.B.dylib             	0x91910b86 start_wqthread + 30
Thread 1 crashed with X86 Thread State (32-bit):
  eax: 0x00000004  ebx: 0x91911f96  ecx: 0xb0080d5c  edx: 0x91911942
  edi: 0xa01b11ec  esi: 0xb0080ed8  ebp: 0xb0080ef8  esp: 0xb0080d5c
   ss: 0x0000001f  efl: 0x00000247  eip: 0x91911942   cs: 0x00000007
   ds: 0x0000001f   es: 0x0000001f   fs: 0x0000001f   gs: 0x00000037
  cr2: 0xb010300c
Binary Images:
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  0xb7b000 -   0xb7dfff +com.yourcompany.yourcocoaframework ??? (1.0) /Applications/AMNESIA - THE DARK DECENT/Amnesia.app/Contents/Resources/Amnesia.app/Contents/Frameworks/ALUT.framework/Versions/A/ALUT
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0x9396e000 - 0x93a16ffb  com.apple.QD 3.35 (???) <B80B64BC-958B-DA9E-50F9-D7E8333CC5A2> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/QD.framework/Versions/A/QD
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0x95062000 - 0x950abfe7  libTIFF.dylib ??? (???) <9CFF48CC-4852-4D06-17AC-3C947C824159> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ImageIO.framework/Versions/A/Resources/libTIFF.dylib
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0x95102000 - 0x95148ff7  libauto.dylib ??? (???) <85670A64-3B67-8162-D441-D8E0BE15CA94> /usr/lib/libauto.dylib
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0x95470000 - 0x95470ff7  liblangid.dylib ??? (???) <B99607FC-5646-32C8-2C16-AFB5EA9097C2> /usr/lib/liblangid.dylib
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0x95d1e000 - 0x95d32fe7  libbsm.0.dylib ??? (???) <14CB053A-7C47-96DA-E415-0906BA1B78C9> /usr/lib/libbsm.0.dylib
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0x95fb8000 - 0x960c4ff7  libGLProgrammability.dylib ??? (???) <1B315838-F477-5416-7504-67EC3433AD4A> /System/Library/Frameworks/OpenGL.framework/Versions/A/Libraries/libGLProgrammability.dylib
0x960c5000 - 0x960d1ff7  libkxld.dylib ??? (???) <322A4B52-8305-3081-6B74-813C3A87A56D> /usr/lib/system/libkxld.dylib
0x96145000 - 0x962c7fe7  libicucore.A.dylib 40.0.0 (compatibility 1.0.0) <2314BD12-0821-75BB-F3BC-98D324CFD30A> /usr/lib/libicucore.A.dylib
0x96827000 - 0x96955fe7  com.apple.CoreData 102.1 (251) <E6A457F0-A0A3-32CD-6C69-6286E7C0F063> /System/Library/Frameworks/CoreData.framework/Versions/A/CoreData
0x96a28000 - 0x96a2bff7  libCGXType.A.dylib 543.50.0 (compatibility 64.0.0) <3B49AED9-0DBA-9D21-F9AC-8784363AD762> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/CoreGraphics.framework/Versions/A/Resources/libCGXType.A.dylib
0x96a2c000 - 0x96a54ff7  libxslt.1.dylib 3.24.0 (compatibility 3.0.0) <769EF4B2-C1AD-73D5-AAAD-1564DAEA77AF> /usr/lib/libxslt.1.dylib
0x96a55000 - 0x96a73ff7  com.apple.CoreVideo 1.6.1 (45.4) <E0DF044D-BF31-42CE-B690-FD1FCE07E64A> /System/Library/Frameworks/CoreVideo.framework/Versions/A/CoreVideo
0x96bde000 - 0x96bf6ff7  com.apple.CFOpenDirectory 10.6 (10.6) <1537FB4F-C112-5D12-1E5D-3B1002A4038F> /System/Library/Frameworks/OpenDirectory.framework/Versions/A/Frameworks/CFOpenDirectory.framework/Versions/A/CFOpenDirectory
0x96bf7000 - 0x96bfeff3  com.apple.print.framework.Print 6.1 (237.1) <97AB70B6-C653-212F-CFD3-E3816D0F5C22> /System/Library/Frameworks/Carbon.framework/Versions/A/Frameworks/Print.framework/Versions/A/Print
0x96bff000 - 0x974dfff7  com.apple.AppKit 6.6.6 (1038.29) <6F28C335-6DC2-AE0E-B79A-F256DBD0BB45> /System/Library/Frameworks/AppKit.framework/Versions/C/AppKit
0x974e0000 - 0x97560feb  com.apple.SearchKit 1.3.0 (1.3.0) <9E18AEA5-F4B4-8BE5-EEA9-818FC4F46FD9> /System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/SearchKit.framework/Versions/A/SearchKit
0x97561000 - 0x975c5ffb  com.apple.htmlrendering 72 (1.1.4) <4D451A35-FAB6-1288-71F6-F24A4B6E2371> /System/Library/Frameworks/Carbon.framework/Versions/A/Frameworks/HTMLRendering.framework/Versions/A/HTMLRendering
0x975fb000 - 0x97606ff7  libGL.dylib ??? (???) <B87E0676-F5EF-8DA3-6DEE-13C43B3832A7> /System/Library/Frameworks/OpenGL.framework/Versions/A/Libraries/libGL.dylib
0x97607000 - 0x97df6557  com.apple.CoreGraphics 1.545.0 (???) <DCED8E1A-7504-C31A-B6EF-98BFF1A61060> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/CoreGraphics.framework/Versions/A/CoreGraphics
0x97e81000 - 0x97ec3ff7  libvDSP.dylib 268.0.1 (compatibility 1.0.0) <3F0ED200-741B-4E27-B89F-634B131F5E9E> /System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libvDSP.dylib
0x97ec4000 - 0x9822cff7  com.apple.QuartzCore 1.6.2 (227.22) <4288F0D2-0C87-F054-C372-8764B44DE024> /System/Library/Frameworks/QuartzCore.framework/Versions/A/QuartzCore
0x9822d000 - 0x98308fe7  com.apple.DesktopServices 1.5.7 (1.5.7) <A69072AD-C47E-A00D-4A69-6E46A7FB2119> /System/Library/PrivateFrameworks/DesktopServicesPriv.framework/Versions/A/DesktopServicesPriv
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0x9884b000 - 0x9886dfef  com.apple.DirectoryService.Framework 3.6 (621.3) <05FFDBDB-F16B-8AC0-DB42-986965FCBD95> /System/Library/Frameworks/DirectoryService.framework/Versions/A/DirectoryService
0x9886e000 - 0x98878ffb  com.apple.speech.recognition.framework 3.11.1 (3.11.1) <EC0E69C8-A121-70E8-43CF-E6FC4C7779EC> /System/Library/Frameworks/Carbon.framework/Versions/A/Frameworks/SpeechRecognition.framework/Versions/A/SpeechRecognition
0x98879000 - 0x9888dffb  com.apple.speech.synthesis.framework 3.10.35 (3.10.35) <57DD5458-4F24-DA7D-0927-C3321A65D743> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/SpeechSynthesis.framework/Versions/A/SpeechSynthesis
0x9888e000 - 0x988cfff7  libRIP.A.dylib 543.50.0 (compatibility 64.0.0) <8BAE1FC1-A478-F151-17C7-2D5DE470AC4F> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/CoreGraphics.framework/Versions/A/Resources/libRIP.A.dylib
0x98a00000 - 0x98a15fff  com.apple.ImageCapture 6.0 (6.0) <3F31833A-38A9-444E-02B7-17619CA6F2A0> /System/Library/Frameworks/Carbon.framework/Versions/A/Frameworks/ImageCapture.framework/Versions/A/ImageCapture
0x98b5a000 - 0x98b5aff7  com.apple.Accelerate.vecLib 3.6 (vecLib 3.6) <1DEC639C-173D-F808-DE0D-4070CC6F5BC7> /System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/vecLib
0x98bf8000 - 0x98c19fe7  com.apple.opencl 12.1 (12.1) <DA2AC3FA-ED11-2D10-21E9-7BDF4778B228> /System/Library/Frameworks/OpenCL.framework/Versions/A/OpenCL
0x98c1a000 - 0x98c5eff3  com.apple.coreui 2 (114) <29F8F1A4-1C96-6A0F-4CC2-9B85CF83209F> /System/Library/PrivateFrameworks/CoreUI.framework/Versions/A/CoreUI
0x98c9d000 - 0x98d35fe7  edu.mit.Kerberos 6.5.10 (6.5.10) <8B83AFF3-C074-E47C-4BD0-4546EED0D1BC> /System/Library/Frameworks/Kerberos.framework/Versions/A/Kerberos
0x99160000 - 0x99180fe7  libresolv.9.dylib 41.0.0 (compatibility 1.0.0) <751955F3-21FB-A03A-4E92-1F3D4EFB8C5B> /usr/lib/libresolv.9.dylib
0x99181000 - 0x991a5ff7  libJPEG.dylib ??? (???) <5CE96981-6B2A-D15B-4A17-E7BD329095B6> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ImageIO.framework/Versions/A/Resources/libJPEG.dylib
0x991a6000 - 0x991a6ff7  com.apple.Carbon 150 (152) <9252D5F2-462D-2C15-80F3-109644D6F704> /System/Library/Frameworks/Carbon.framework/Versions/A/Carbon
0x992a3000 - 0x9933eff7  com.apple.ApplicationServices.ATS 275.11.1 (???) <5FF65EC7-F512-530A-7771-3DE240EE6E43> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ATS.framework/Versions/A/ATS
0x993dd000 - 0x993ebff7  com.apple.opengl 1.6.9 (1.6.9) <4F06C166-00CF-5ACF-77E3-5A960A5E8AD3> /System/Library/Frameworks/OpenGL.framework/Versions/A/OpenGL
0x993ef000 - 0x99422ff7  com.apple.AE 496.4 (496.4) <7F34EC47-8429-3077-8158-54F5EA908C66> /System/Library/Frameworks/CoreServices.framework/Versions/A/Frameworks/AE.framework/Versions/A/AE
0x99423000 - 0x99423ff7  com.apple.CoreServices 44 (44) <AC35D112-5FB9-9C8C-6189-5F5945072375> /System/Library/Frameworks/CoreServices.framework/Versions/A/CoreServices
0x99430000 - 0x99432ff7  libRadiance.dylib ??? (???) <AB06F616-E3EA-5966-029A-8AA44BBE5B28> /System/Library/Frameworks/ApplicationServices.framework/Versions/A/Frameworks/ImageIO.framework/Versions/A/Resources/libRadiance.dylib
0x99433000 - 0x99435ff7  com.apple.securityhi 4.0 (36638) <38D36D4D-C798-6ACE-5FA8-5C001993AD6B> /System/Library/Frameworks/Carbon.framework/Versions/A/Frameworks/SecurityHI.framework/Versions/A/SecurityHI
0x99436000 - 0x9943bff7  com.apple.OpenDirectory 10.6 (10.6) <92582807-E8F3-3DD9-EB42-4195CFB754A1> /System/Library/Frameworks/OpenDirectory.framework/Versions/A/OpenDirectory
0x9943c000 - 0x9943dff7  com.apple.audio.units.AudioUnit 1.6.3 (1.6.3) <959DFFAE-A06B-7FF6-B713-B2076893EBBD> /System/Library/Frameworks/AudioUnit.framework/Versions/A/AudioUnit
0x9943e000 - 0x99854ff7  libBLAS.dylib 219.0.0 (compatibility 1.0.0) <C4FB303A-DB4D-F9E8-181C-129585E59603> /System/Library/Frameworks/Accelerate.framework/Versions/A/Frameworks/vecLib.framework/Versions/A/libBLAS.dylib
0xffff0000 - 0xffff1fff  libSystem.B.dylib ??? (???) <3441F338-2218-6D36-3F95-3A16FBF6713D> /usr/lib/libSystem.B.dylib
Model: iMac9,1, BootROM IM91.008D.B08, 2 processors, Intel Core 2 Duo, 2.66 GHz, 2 GB, SMC 1.36f3
Graphics: NVIDIA GeForce 9400, NVIDIA GeForce 9400, PCI, 256 MB
Memory Module: global_name
AirPort: spairport_wireless_card_type_airport_extreme (0x14E4, 0x8E), Broadcom BCM43xx 1.0 (5.10.91.27)
Bluetooth: Version 2.3.3f8, 2 service, 19 devices, 1 incoming serial ports
Network Service: Ethernet, Ethernet, en0
Network Service: AirPort, AirPort, en1
Serial ATA Device: Hitachi HDT721032SLA380, 298.09 GB
Serial ATA Device: OPTIARC DVD RW AD-5670S
USB Device: My Book, 0x1058  (Western Digital Technologies, Inc.), 0x1100, 0x26400000
USB Device: iPad, 0x05ac  (Apple Inc.), 0x129a, 0x24100000
USB Device: Built-in iSight, 0x05ac  (Apple Inc.), 0x8502, 0x24400000
USB Device: Keyboard Hub, 0x05ac  (Apple Inc.), 0x1006, 0x24300000
USB Device: Apple Keyboard, 0x05ac  (Apple Inc.), 0x0221, 0x24320000
USB Device: BRCM2046 Hub, 0x0a5c  (Broadcom Corp.), 0x4500, 0x06100000
USB Device: Bluetooth USB Host Controller, 0x05ac  (Apple Inc.), 0x8215, 0x06110000
USB Device: IR Receiver, 0x05ac  (Apple Inc.), 0x8242, 0x04500000
I hope this information helps.  Is there anything you can do to help me, since I may not be able to continue otherwise, and I've been thoroughly enjoying this game!
I'll try it a few more times, but I suspect the result will be the same.  If you can help me here it would be very much appreciated.
Thanks.