Multiplayer/Co-Op & Frictional Games? NO!!!

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These suggestions would be great, but NOT for Co-op, instead having NPC
followers in the game, that you could help or hinder, moral choices and
consequences, a trust/loyalty system!

Ummm...I'm...not so sure about that. I can't remember a single game where NPC followers weren't a constant source of annoyance and ragequits for me. Mostly due to their bad AI. I mean the monster AI was already bad enough in Amnesia and while that didn't hurt gameplay - do you really need an NPC follower that gets stuck on ledges, annoys you with constantly repeated lines of monologue, misinterprets your commands and makes you lose the game every time he obliviously stumbles into the arms of some Lovecraftian monstrosity?

I also agree that having a companion always diminishes the feeling of being desperate and alone somewhat. So while I think the ideas mentioned are great - especially the voicechat bits - I don't think Amnesia is the right game for them. It relies too heavily on the feeling of loneliness for its horror to work.

But if anyone knows the game Journey on the playstation then perhaps
something could be learned from it's construction. I have long thought
the idea of multiplayer anonymity and limited communication could be
very valuable and has been slowly emerging in recent games.

Yup, Journey is awesome. Everyone should play it, it would make the world a better place Not sure how one could implement that into a horror game though... hm, maybe like this: You randomly get connected with another player (like Journey does), so you'll sometimes unknowingly share the level with someone else. The thing is, that sometimes (maybe depending on current insanity) your or his appearance and sounds will be that of a monster instead of a friendly player. Of course neither of you knows what his character actually looks like so combined with the lack of communication there would be plenty of room for misunderstandings
On second thought, players would probably just troll each other...