Are there any apart from the mentioned below?
I've just bought my first nvidia card in years and some of the global defaults make me scratch my head. Like SSAO:Off for example.
My GPU is GF 660 Ti by MSI (msi 660ti power edition N660Ti_PE_2GD5OC)
CPU: AMD FX-6300
1.
Threaded optimizations
https://www.frictionalgames.com/forum/thread-30627.html
2.
Shader cache setting
https://www.frictionalgames.com/forum/thread-30715.html
My personal note on
Vsync:
I went ahead and disabled vsync completely. It's weird but the inherent tearing that obviously started appearing is not bothersome at all. It's different than in any other game I've seen. It almost looks like a slight deliberate glitch effect.
A test on #1 and #2:
They don't seem to have any effect on my system (355.82 driver version)