For some reason going through doors randomly causes the game to slow down to less than 1 FPS.
I can't find a pattern to it, but once it has happened with a specific area the only way to fix it has been to exit, start and change resolution, then restart again and play at new resolution. If I am currently in the room that is running slowly and I have a save point within the room, just reloading that save will also fix it.
Possibly of note is the installer gives me the "Couldn't find any suitable frontend for your system" error, but I just ran the installer with the --tar option and installed it with the startupinstaller.sh
Computer is nvidia 7800GT with latest nvidia drivers, gentoo x86_64 with 2.6.33.3 kernel. As far as I can tell all 32 bit libraries are installed.
$ find /usr/lib{,32,64} -name "libstdc*so.*"
/usr/lib32/libstdc++.so.2.7.2.8
/usr/lib32/libstdc++.so.5
/usr/lib32/libstdc++-libc6.2-2.so.3
/usr/lib32/libstdc++.so.2.8
/usr/lib32/libstdc++.so.2.9
/usr/lib32/libstdc++.so.2.7.2
/usr/lib32/libstdc++.so.2.8.0
/usr/lib32/libstdc++.so.2.9.0
/usr/lib32/libstdc++.so.5.0.7
/usr/lib32/libstdc++-libc6.1-1.so.2
/usr/lib64/gcc/x86_64-pc-linux-gnu/4.4.3/32/libstdc++.so.6.0.13
/usr/lib64/gcc/x86_64-pc-linux-gnu/4.4.3/32/libstdc++.so.6
/usr/lib64/gcc/x86_64-pc-linux-gnu/4.4.3/libstdc++.so.6.0.13
/usr/lib64/gcc/x86_64-pc-linux-gnu/4.4.3/libstdc++.so.6
/usr/lib64/libstdc++.so.5
/usr/lib64/libstdc++.so.5.0.7
$ file -L /usr/lib32/libstdc++.so.5
/usr/lib32/libstdc++.so.5: ELF 32-bit LSB shared object, Intel 80386, version 1 (SYSV), dynamically linked, stripped